Phenylpropanoids and polyketides
Medchemexpress LLC m-Coumaric acid (Standard) | 588-30-7 | 99.9% | 164.16 | 100 MG
m-Coumaric acid (Standard) | 588-30-7 | 99.9% | 164.16 | 100 MG
Selleck Chemical LLC BLU 451-E1877-100MG
BLU 451 is a central nervous system (CNS)-penetrant wild-type EGFR-sparing covalent inhibitor of epidermal growth factor receptor (EGFR) exon 20 insertion (Ex20ins) with an IC50 of 7-78 nM It also exhibits a potent anti-tumor efficacy
Medchemexpress LLC p-Coumaric acid (standard) | 501-98-4 | 164.16 | 100 MG
p-Coumaric acid (Standard) is the analytical standard of p-Coumaric acid, intended for research and analytical applications. It is an isomer of cinnamic acid with oral activity. p-Coumaric acid inhibits cell proliferation, promotes apoptosis, and exhibits antibacterial, anti-inflammatory, antioxidant, and anti-tumor activities.
- Analytical standard for research and analytical applications
- Inhibits cell proliferation and promotes apoptosis
- Exhibits antibacterial, anti-inflammatory, antioxidant, and anti-tumor activities
- Used as a reference standard in qualitative, quantitative, and methodological research experiments
- Suitable for HPLC, GC, and MS applications
Medchemexpress LLC p-Coumaric acid (trans-4-hydroxycinnamic acid) | 501-98-4 | 164.16 | 10 G
p-Coumaric acid, an isomer of cinnamic acid, demonstrates diverse biological activities including antibacterial, anti-inflammatory, antioxidant, and anti-tumor effects. It has been shown to inhibit cell proliferation and promote apoptosis, making it a subject of interest in various research applications.
- Inhibits proliferation of A375 and B16 cells.
- Promotes cell apoptosis in human and mouse melanoma cells.
- Exhibits antibacterial activity against gram-negative and gram-positive bacteria.
- Reduces polyp incidence and precancerous lesions in animal models.
- Alleviates doxorubicin-induced nephrotoxicity by inhibiting oxidative stress, inflammation, and apoptosis.
- Modulates cell cycle progression and protein expression in A375 and B16 cells.
Medchemexpress LLC p-Coumaric acid ethyl ester | 7362-39-2 | MFCD00210460 | 50 MG
p-Coumaric Acid Ethyl Ester is a non-competitive, reversible inhibitor of tyrosinase. It quenches the intrinsic fluorescence of the enzyme and changes the binding affinity of L-tyrosine by inducing conformational changes in the catalytic domain of tyrosinase, without binding to the copper ion of the enzyme. This compound is utilized in the development of medicines, cosmetics, and for fruit preservation.
- Non-competitive, reversible inhibitor of tyrosinase
- Quenches the intrinsic fluorescence of the enzyme
- Induces conformational changes in the catalytic domain of tyrosinase without binding to copper ion
- Exhibits anti-platelet activity in rabbit platelet-rich plasma
- Utilized in medicine and cosmetic development
- Used for fruit preservation
Medchemexpress LLC Ferulic acid methyl ester | 2309-07-1 | 99.9% | 208.21 g/mol | C11H12O4 | 1 G
Ferulic acid methyl ester (methyl ferulate) is the methyl ester derivative of ferulic acid used as a research reagent. It is reported as a p38 MAPK inhibitor with anti-inflammatory and antioxidant properties and is applied in studies of autophagy and neurological disease. The compound is cell membrane and brain permeable and modulates COX-2, p-p38, and p-JNK signaling.
- CAS number 2309-07-1
- Chemical formula C11H12O4
- Molecular weight 208.21 g/mol
- Typical purity ~99.9% (rounded)
- Available as solid and 10 mM solution in DMSO
- Reported p38 MAPK inhibitor with anti-inflammatory activity
- Useful for autophagy and neurological disease research